© РИА Томск. Павел Стефанский
TOMSK, Feb 13 – RIA
Tomsk. Tomsk Polytechnic University scientists together with
Russian and foreign colleagues proposed to apply superhydrophilic coating of
spherical calcium phosphate nanoparticles to medical implants of titanium,
vanadium, aluminum alloy to reduce risk of implant rejection and protect from
toxicity, the press service of the university said on Wednesday.
It is noted that the
alloy of titanium, aluminum and vanadium (VT6) - one of the most common for the
manufacture of implants. However, cells of the body poorly interact with
titanium, and it can be rejected, while vanadium and aluminum are toxic.
"We propose to use
a coating made of spherical calcium phosphate nanoparticles. This compound - is
the mineral component of human bone. Therefore the body does not perceive it as
a foreign element. On the one hand, the coating provides protection from
aluminum and vanadium, on the other - increases the biocompatibility of the
entire implant", - the research engineer Ekaterina Chudinova is quoted in
the message.
It is added that
calcium phosphate nanoparticles make the implant surface super-hydrophilic - it
is well wetted with fluids and the body interacts better with the device
embedded in it. The innovation of the work lies in the fact that the Tomsk
scientists were the first to apply a calcium phosphate coating to the
three-metal alloy and obtain a super-hydrophilic coating.
© РИА Томск. Таисия Воронцова
The research was
supported by a grant of the Russian Science Foundation and Russian Foundation
for Basic Research (RFBR). The work is carried out at the TPU Research School
of Chemistry & Applied Biomedical Sciences in collaboration with Mid Sweden
University, University of Duisburg-Essen (Germany), Peter the Great
St.Petersburg Polytechnic University and First Pavlov State Medical University
of St. Petersburg.
Tomsk Polytechnic University
- is the leading technical university of the country. It's founded in 1896 as
Tomsk Technological Institute of Practical Engineers of Emperor Nicholas II. He
became the first engineering university in the Asian part of the country. Today
TPU enters the top 10 universities of Russia and the top 400 universities of
the world.