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6:42 PM  March 19, 2019

TSU look for congenital CNS abnormalities new diagnostic methods

© с сайта Томского госуниверситетаTSU look for congenital CNS abnormalities new diagnostic methods

TOMSK, Mar 19 – RIA Tomsk. Neuroscientists of Tomsk State University (TSU) are developing methods for early diagnosis of maturation and damage of myelin (the substance of nervous fibers cover) in children, including prenatal period, to determine the developmental delay of children and predict intellectual abilities, the press service of the university reports on Tuesday.

With reference to Vasily Yarnykh, Professor of TSU and the University of Washington, it is explained that congenital malformations of the fetus are among the three main causes of perinatal mortality and neonatal death. Most of the anomalies are caused by the interaction of genetic and environmental factors, and effective methods are needed for the early diagnosis of severe diseases of the central nervous system (CNS).

"For the solution of this problem TSU scientists suggest to use mapping of myelin - one of the main components of the brain substance that provides conduction of nerve impulses and protecting nerve fibers from damage ... Scientists start searching for biomarkers of maturation and damage to the brain matter in children, including the fetus after 20th week of pregnancy", - is said in the statement.

Diagnostics of violations of myelination at an early age is important for "isolating at-risk groups of patients with mental retardation, autism and more serious mental illnesses, which, in turn, can be used to prescribe early behavioral therapy and develop social adaptation skills", - the press service explains.

© пресс-служба Томского госуниверситета
It is noted that for the first time a non-invasive method for myelin evaluating was developed several years ago by a group of scientists under the leadership of Yarnykh. Now it is being tested in several clinics in Russia, including to assess damage to the sheaths of nerve fibers in people who have suffered a stroke. In 2018, this method was also tested when examining children in their first years of life and fetuses in the process of prenatal development.

The study of Tomsk scientists received the support of the Russian Science Foundation and is designed for four years.

Наверх
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