13 декабря 2019  |  
9:01 PM  August 13, 2019

TPU and German scientists create open source software for biomedicine

© Маргарита ВолоковыхTPU and German scientists create open source software for biomedicine

TOMSK, Aug 13 – RIA Tomsk. Employees of Tomsk Polytechnic University (TPU) and Karlsruhe Institute of Technology (Germany) have developed software that analyzes scaffolds – a polymer base for growing new organs and tissues; this is the first publicly available software for the study of polymer and hybrid materials, the press service of the university said on Tuesday.

According to the university, scaffolds – are promising area in biomedicine. They are materials made of thin polymer threads interwoven with each other. They are placed at the site of a bone defect, for example, fracture, as a framework for new bone cells. New bone tissue grows through the scaffold and fills the fracture site. When the bone is completely restored, the polymer dissolves in the body.

"Quanfima software analyzes the structure of polymer frameworks, which serve as the basis for the growth of new organs and tissues. Unlike existing analogs, this is the first publicly available software which analyzes different types of biomaterials: polymer scaffolds or hybrid polymer scaffolds, which contain the microdispersed inorganic phase", – is said in the statement.

According to one of the authors of the study, the Director of the TPU Research Center for Physical Materials Science and Composite Materials Roman Surmenev, composite three-dimensional scaffolds, represented by various materials with a fibrous structure or containing various additives, have a positive effect on the regeneration of various tissues.

The need for software development, according to polytechnicians, is due to the lack of a free software product for the analysis of fibers in terms of their orientation in space relative to the selected basis and size.

© Маргарита Волоковых
"A number of foreign scientific groups have commercial products which functionality is similar to the program we developed, but they are not in the public domain", – the scientist is quoted in the message.

International tandem

According to the university, the work was carried out in the framework of the international scientific group. Software was created on the basis of the programming language Python by employee of Karlsruhe Institute of Technology Roman Shkarin. Polytechnicians in turn, provided model materials for research – polymer scaffold and hybrid polymer scaffold.

The Quanfima software package, according to the developers, is based on several widely distributed products designed for data analysis, for example, NumPy, SciPy, scikit-image, VIGRA, Pandas and Statsmodels. In the new software scientists have tried to combine their capabilities.

"At present, Quanfima software ("Quantitative Analysis of Fibrous Materials") has been developed and can be used for its intended purpose. The product can be downloaded by clicking the link. Our program allows to analyze parameters that are key for any biomaterial when used in regenerative medicine", – Surmenev summarized.

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