TOMSK, Sep 29 – RIA Tomsk. Scientists of Siberian State Medical University (SSMU) and Moscow State University develop a cure for high blood pressure (hypertension) with a fundamentally new mechanism of action; such drugs weren't on the world market for about 15 years, the press service of the region innovative organizations reports on Thursday.
"All the medicines lowering the pressure work approximately the same, affecting long ago known targets. Our team of chemists managed to synthesize a substance with the new mechanism of action therefore medicine we are working on has no analogs", – the press service quotes the vice rector of SSMU for scientific work and postdegree preparation Svetlana Gusakova.
It is explained that substance on the basis of which the medicine is created is chemical "predecessor" of PAF (platelet activating factor). PAF itself scientists synthesized in the second half of the last century, having described its ability to reduce arterial pressure. But unlike the PAF, the "preceding" substance works long and doesn't influence blood coagulability."It is the Russian medicine which is created not as an analog of existing. It has absolutely new mechanism of action, a new target. For the last 10-15 years it is the only again synthesized medicine for treatment of a hypertension, but not the combination of already known", – Gusakova specified.
In the message it is said that medicine is nontoxical. It acts within a day, therefore one tablet daily to the person is enough. Medicine doesn't lower pressure if it is normal, but normalizes the raised indicators. It doesn't cause accustoming. Scientists believe that medicine will affect hypertension forms which don't give in to correction yet.
It is noted that scientists will need a year more on registration of medicine and about three years for clinical tests. Medicine will enter the market not earlier than in five years – terms depend on financing. It is expected that its cost won't exceed the price of the existing hypertension medicines, and in case of successful tests medicine will go for export.