© РИА Томск. Олег Асратян
TOMSK, Sep 29 –
RIA Tomsk. Scientists of Siberian State Medical University
(SSMU) and Moscow State University develop a cure for high blood pressure
(hypertension) with a fundamentally new mechanism of action; such drugs weren't
on the world market for about 15 years, the press service of the region
innovative organizations reports on Thursday.
"All the medicines lowering
the pressure work approximately the same, affecting long ago known targets. Our
team of chemists managed to synthesize a substance with the new mechanism of
action therefore medicine we are working on has no analogs", – the press
service quotes the vice rector of SSMU for scientific work and postdegree
preparation Svetlana Gusakova.
© flickr.com/ Jason Rogers
It is explained that substance
on the basis of which the medicine is created is chemical
"predecessor" of PAF (platelet activating factor). PAF itself
scientists synthesized in the second half of the last century, having described
its ability to reduce arterial pressure. But unlike the PAF, the
"preceding" substance works long and doesn't influence blood
coagulability.
"It is the Russian
medicine which is created not as an analog of existing. It has absolutely new
mechanism of action, a new target. For the last 10-15 years it is the only
again synthesized medicine for treatment of a hypertension, but not the
combination of already known", – Gusakova specified.
In the message it is said that
medicine is nontoxical. It acts within a day, therefore one tablet daily to the
person is enough. Medicine doesn't lower pressure if it is normal, but
normalizes the raised indicators. It doesn't cause accustoming. Scientists
believe that medicine will affect hypertension forms which don't give in to
correction yet.
It is noted that scientists
will need a year more on registration of medicine and about three years for
clinical tests. Medicine will enter the market not earlier than in five years –
terms depend on financing. It is expected that its cost won't exceed the price
of the existing hypertension medicines, and in case of successful tests
medicine will go for export.