© предоставлено пресс-службой Томского госуниверситета
TOMSK, 19 Dec – RIA Tomsk. Scientists of Tomsk State University (TSU)
together with colleagues from the Krasnoyarsk State Medical University
(KrasSMU) create new test system which allow to tap not one, but six oncomarker
in blood of a person at once that make diagnostics of lung cancer faster and
more reliable, the press service of TSU reports.
It is specified that the low-invasive method of simultaneous identification
of several proteins-onсomarkers in plasma of blood of a person was developed by
scientists of KrasSMU. Working off of the method takes place on the basis of
the Siberian Physics and Technology Institute (SPTI) of TSU.
"The new test system represents the chip with gold electrodes to which
six various aptamer are attached – the parts of molecules of DNA capable to
contact strongly various oncomarkers. In the course of diagnostics blood plasma
is applied on the chip. If there are specific proteins, they contact DNA within
30 minutes. After that scientists read out the signal arriving from
aptamer", – it is said in the message.
© РИА Томск. Яков Андреев
It is explained with reference to the senior research associate of the
laboratory of new materials and perspective technologies of the SPTI Anastasiya
Shabalina that the signal of the test will be different depending on existence
or lack of protein-oncomarker in blood plasma.
"Our task is to receive and process a signal, and also to calculate
errors. These data are necessary to find out how it is possible to increase,
for example, the accuracy and sensitivity of the method", – Shabalina is
quoted in the message.
Scientists of the SPTI also look for an opportunity to simplify procedure
of the analysis. In particular, they try to replace preliminary cleaning of
electrodes with caustic mix with more sparing process of electrochemical
preparation.