TSU chemists with colleagues created domestic films against adhesions

TOMSK, Apr 6 – RIA Tomsk. Scientists of Tomsk State University (TSU) together with their colleagues created an anti-adhesion material that is superior in efficiency to foreign analogues, but at the same time is 10 times cheaper; the development will help doctors solve the problem of adhesions in patients after surgery, the university's website said on Tuesday.

It is specified that in addition to TSU, scientists of the Institute for Problems of Chemical and Energetic Technologies of the Siberian Branch of the Russian Academy of Sciences (IPCET SB RAS, Biysk) and Siberian State Medical University (SSMU) are participating in the project. In March 2021, chemists received a patent for a new material.

"Biodegradable films, created by Siberian scientists, not only solve the problem of adhesions, but also reduce the risk of developing inflammation in the postoperative period. Currently, the intellectual property rights are transferred to the industrial partner of the project – Engineering Chemical Technological Center (ECTC), which will be engaged in the commercialization of the product," says the message.

It is explained that adhesive disease is a complication that occurs after intracavitary operations. The adhesion of tissues can lead to the death of the patient. The only way to effectively combat adhesive disease is to prevent it. The USA and Europe are the leaders in the production of anti-adhesive agents. The price of an imported anti-adhesive film measuring 13x15 centimeters is about $115. The cost of the material created by Siberian scientists will be less than $10 per film

"Scientists of TSU and IPCET SB RAS have developed an anti-adhesion material based on domestic reagents from renewable natural raw materials – cellulose derivatives. The effectiveness of the material was tested by the employees of Siberian State Medical University in experiments on rats," the TSU website reported.

It is added that the rodents, which were supplied with the film, were completely excluded from adhesion disease, while the rats without the film developed such complication in 80% of cases. It was also found that the biodegradation period of the films is five days, the new material is non-toxic and has an anti-inflammatory effect.